Upon announcing their split, Brad Pitt and Jennifer Aniston released a joint statement, debunking the tabloid rumors that the actor had cheated on his estranged wife. "For those who follow these sorts of things, we would like to explain that our separation is not the result of any of the speculation reported by the tabloid media. This decision is the result of much thoughtful consideration," the actors said in their statement (via Marie Claire.) However, the speculation wouldn't stop, especially after Pitt began dating Angelina Jolie, with the pair seeming to move very quickly.

Pitt and Aniston's divorce was finalized in 2005 and the following year, he welcomed his first biological child with Jolie, a daughter named Shiloh. The pair went on to welcome twins Vivienne and Knox, and shared adopted children Maddox, Pax, and Zahara. Pitt and Jolie got married in 2014, and Aniston later married Justin Theroux. Both marriages eventually ended in divorce.

In 2007, Pitt again refuted the claims that he was unfaithful to Aniston during an interview on "Larry King Live," per the New Zealand Herald. When King suggested that Pitt and Jolie became romantically involved while working together when Pitt was still married to Aniston, the actor denied the rumors. "That came after, Larry. That came after," he said of his relationship with Jolie.