Coco was brought into existence during the debut of a sketch called "Twitter Tracker," in which the announcer continued to annoy Conan O'Brien by calling him "bro" (via The Wrap). "Bro's a no-no for CoCo?" the mysterious voice asked the comedian. "Don't call me Coco," the comedian replied. It wasn't brought up again until guest Tom Hanks reacted to O'Brien's middle name later on in the show. Retitling "The Tonight Show" as "The Coco Christopher Show," Hanks inadvertently made the name stick by making the audience chant it (via YouTube).

Even when there was a big feud between O'Brien and Jay Leno, "I'm with CoCo" became a rallying cry for those on O'Brien's side (via HuffPost and Entertainment Weekly). "You ruined my life," O'Brien told Hanks when he came back on the show a year later. "It's a sample of my power," Hanks replied, hilariously adding that at least O'Brien will "finally blame something on someone other than Jay."