The first part, "A New World", tells how the young German engineer Karl May comes to America and starts to work for a railway company in the Wild West. Under dramatic circumstances, he meets Apache chief Winnetou and becomes friends with him and his tribe. The Apaches give it the name Old Shatterhand. Together they fight now against the unscrupulous henchmen of the railway company, who wants to lay a route through the Indian area.

In Part Three, entitled "The Last Fight," gangster Santer Jr. attempts to seize an oil well on Indian territory. To prevent this, Winnetou and Old Shatterhand must reconcile the warring Indian tribes so that they can take up the fight against the henchmen of the criminal.

In a future not too far away, Steve Battier, an elderly, terminally ill multi-millionaire, accepts the offer of a company - RPG - that in exchange for a high monetary sum, provides a very select group of clientèle the chance to be young again. For 10 hours, 10 millionaires from around the world, men and women of fame and power, are transferred to attractive and healthy younger bodies, to live in a world of temporary rejuvenation, in a game of real thrills, where every hour someone must die.