“Retinol has multiple positive effects on the skin,” explains Brooke Jeffy, dermatologist and founder of youth skincare brand BTWN. “It improves skin cell turnover and unclogs pores to help acne and improves skin texture. Retinol reduces collagen breakdown and stimulates production, resulting in reduction of fine lines, and can improve the appearance of brown spots.”

For the best results, start slow, using retinol two to three times per week and increase gradually every three weeks, up to nightly use. “Pair your retinol with a moisturizer to improve tolerability,” Jeffy says. “In general, avoid using products with ingredients including benzoyl peroxide, alpha and beta hydroxy acids, and vitamin C at the same time as retinol, to improve tolerability.”