Rosie O'Donnell would make a return to daytime television in 2006 when she co-hosted "The View," but her time on the show would be short. In 2007, she left after not being able to commit to a contract, according to ABC News. However, according to Entertainment Tonight, O'Donnell had a tumultuous time on the show, often clashing politically with co-host Elisabeth Hasselbeck. She would continue her "angry" persona in the media. 

In 2015, O'Donnell tried coming back to "The View" again, but couldn't make it work. According to Variety, O'Donnell claimed it was "the end of her second marriage" that caused her to step away. However, it was reported her reputation as "demanding and sometimes abrasive" was also a factor. 2015 was supposed to be a comeback year for O'Donnell, who also had a huge weight loss transformation. According to ABC News, the comedian underwent gastric-bypass surgery "after having a heart attack and nearly dying." She said that despite losing more than 50 pounds, she still didn't feel "beautiful." She said that the surgery was more about her health than anything, and her heart attack caused her to refocus on a less stressful life. By quitting "The View" and spending more time with her family, O'Donnell could get back to healthy living.